RAF Typhoon FGR4s have conducted a mission with French warplanes in a joint strike against an subterranean weapons facility in Syrian territory employed by the IS group, per a report from the British defence ministry.
The facility, located using surveillance, was believed to be containing munitions and bombs, the announcement noted, and was located in hills just to the north of the historic site of Palmyra in the heart of Syria.
"Our fighter planes utilized precision-guided Paveway IV munitions to hit a series of access tunnels leading to the site... initial indications indicate the target was engaged successfully," the MoD said.
There was no indication of any harm to civilians in the operation late on Saturday and each participating jet returned safely, the ministry further stated.
The British jets were supported by a Voyager aerial refuelling aircraft.
Daesh - alternatively referred to as ISIS - imposed jihadist rule over parts of Iraq and Syria before its territorial defeat in 2019.
"This action demonstrates British leadership, and determination to work closely with allied nations, to eradicate any revival of IS and their harmful and extremist ideologies in the area," Britain's Defence Chief the Defence Secretary remarked.
British military aircraft have conducted surveillance missions over Syrian airspace to "deter any efforts to regroup" of Islamic State after its defeat at the battle of Baghuz in 2019, the authorities noted.
"I extend gratitude to all the members of our armed forces involved in this strike for their professionalism and their courage," he added. "They were among thousands of British troops on duty over Christmas and New Year. This mission, to remove militants who threaten our security, demonstrates how British military are ready to step up, throughout the year, protecting the UK domestically and influential overseas."
In December, the United States armed forces carried out what it described as a "large-scale strike" on Daesh sites in Syria, after an attack killed two American soldiers and a civilian linguist in the Palmyra area.
The United Nations says Islamic State still has roughly 5-7 thousand fighters in both countries.